Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321358 | 0.79 | KDM4E (0.37) | KMT2AMEN1KDM4EKCNN4CYP2D6 | |
| SCHEMBL5692289 | 0.76 | KDM4E (0.41) | KMT2AMEN1KDM4ECYP2D6 | |
| SCHEMBL9238656 | 0.74 | KDM4E (0.44) | KMT2AMEN1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL20768154 | 0.70 | KMT2A (0.38) | KMT2AMEN1KDM4EKCNN4CYP11B1 | |
| SCHEMBL647893 | 0.68 | KMT2A (0.46) | KMT2AMEN1KCNN4CYP11B1CYP11B2 | |
| SCHEMBL7246865 | 0.67 | KDM4E (0.39) | KDM4ECYP11B1CYP11B2CYP2D6 | |
| SCHEMBL1528022 | 0.65 | KMT2A (0.44) | KMT2AMEN1KCNN4CYP11B1CYP11B2 | |
| SCHEMBL392779 | 0.65 | CYP11B1 (0.43) | KMT2AMEN1KCNN4CYP11B1CYP11B2 | |
| SCHEMBL4543871 | 0.65 | CYP11B1 (0.43) | KMT2AMEN1KCNN4CYP11B1CYP11B2 | |
| SCHEMBL8188378 | 0.65 | KMT2A (0.46) | KMT2AMEN1KCNN4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472260-A2 | THIENO(3,2-B)PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003059878-A2 | THIENO (3, 2-B) PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | disclosed |