Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693656 | 0.84 | KMT2A (0.64) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11489831 | 0.81 | KMT2A (0.60) | MAPTKMT2AKDM4ENAMPTMEN1 | |
| SCHEMBL13885601 | 0.79 | KMT2A (0.76) | MAPTKMT2AKDM4ENAMPTMEN1 | |
| SCHEMBL5353997 | 0.76 | NAMPT (0.51) | MAPTNAMPTL3MBTL1LMNACES2 | |
| SCHEMBL27510637 | 0.76 | LMNA (0.56) | MAPTKMT2AKDM4ENAMPTCNR2 | |
| SCHEMBL14062862 | 0.76 | KMT2A (0.76) | MAPTKMT2AKDM4ENAMPTMEN1 | |
| SCHEMBL29823214 | 0.74 | CA12 (0.61) | MAPTKMT2AKDM4EMEN1LMNA | |
| SCHEMBL2335784 | 0.74 | CES2 (0.53) | MAPTKMT2AMEN1LMNACES2 | |
| SCHEMBL1147208 | 0.74 | CA12 (0.61) | MAPTKMT2AKDM4EMEN1LMNA | |
| SCHEMBL1353510 | 0.73 | KMT2A (0.51) | MAPTKMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941998-B1 | 3,6-ketal macrolide antibiotics | PFIZER PROD INC (US) | 2004-09-01 | — | — | EP | disclosed |
| US-6043226-A | TREATING BACTERIAL, PARASITIC AND PROTOZOAL INFECTIONS | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0941998-A2 | 3,6-ketal and enol ether macrolide antibiotics | Pfizer Products Inc. (US) | 1999-09-15 | — | — | EP | disclosed |