Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416596 | 0.89 | NPSR1 (0.39) | NPSR1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6694014 | 0.83 | NPSR1 (0.43) | NPSR1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6701182 | 0.81 | NPSR1 (0.42) | NPSR1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7361311 | 0.80 | NPSR1 (0.43) | NPSR1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3073692 | 0.80 | ALDH1A1 (0.45) | NPSR1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL458998 | 0.80 | ALDH1A1 (0.46) | NPSR1KMT2AMEN1ALDH1A1PLAU | |
| Hydrochloric Acid SCHEMBL28482173 | 0.79 | ALDH1A1 (0.43) | NPSR1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6695839 | 0.77 | ALDH1A1 (0.49) | NPSR1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6692705 | 0.77 | NPSR1 (0.38) | NPSR1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6691763 | 0.76 | NPSR1 (0.36) | NPSR1KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |