SCHEMBL458998

SCHEMBL458998

N=C(N)N(C(=N)N)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
F2 P00734 1/20 0.46
F10 P00742 1/20 0.46
F12 P00748 1/20 0.46
F7 P08709 1/20 0.46
F3 P13726 1/20 0.46
PKM P14618 1/20 0.46
BLM P54132 1/20 0.44
KMT2A Q03164 2/20 0.42
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
C1S P09871 1/20 0.42
PRSS3 P35030 1/20 0.42
RECQL P46063 1/20 0.42
MEN1 O00255 1/20 0.41
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7361311 0.86 NPSR1 (0.43) ALDH1A1F2F10F12F7
SCHEMBL3073692 0.86 ALDH1A1 (0.45) ALDH1A1F2F10F12F7
SCHEMBL11134255 0.86 ALDH1A1 (0.56) ALDH1A1F2F10F12F7
Hydrochloric Acid SCHEMBL28482173 0.84 ALDH1A1 (0.43) ALDH1A1F2F10F12F7
SCHEMBL6694014 0.81 NPSR1 (0.43) ALDH1A1F2F10F12F7
SCHEMBL6687559 0.81 ALDH1A1 (0.53) ALDH1A1F2F10F12F7
SCHEMBL7075852 0.81 TDP1 (0.49) ALDH1A1F2F10F12F7
SCHEMBL1740828 0.80 ALDH1A1 (0.44) ALDH1A1F2KMT2APRSS1MEN1
SCHEMBL6701182 0.80 NPSR1 (0.42) ALDH1A1F2F10F12F7
SCHEMBL6698602 0.80 NPSR1 (0.42) ALDH1A1F2F10F12F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506207-B1 Pharmaceutical vehicles for reducing transdermal flux ACCESS PHARMA INC (US) 1999-11-17 EP claimed
EP-4180482-B1 MOISTURE-CURABLE COMPOSITION NITTO KASEI CO LTD (JP) 2025-12-03 EP disclosed
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product NITTO KASEI CO., LTD. (JP) 2025-11-25 US disclosed
EP-4174053-B1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO LTD (JP) 2025-11-19 EP disclosed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
CN-115516041-B Curing catalyst for curing polymer, method for producing same, moisture-curable composition, and method for producing cured product 日东化成株式会社 2024-06-28 CN disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO., LTD. (JP) 2023-07-27 US disclosed
EP-4180482-A1 MOISTURE-CURABLE COMPOSITION Nitto Kasei Co., Ltd. (JP) 2023-05-17 EP disclosed
CN-104045976-A Resin composition AJINOMOTO KK 2014-09-17 CN disclosed
WO-2011118818-A8 AMIDINOANILINE DERIVATIVE 味の素株式会社 (JP) 2012-01-26 WO disclosed
EP-2388297-A1 CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM Kaneka Corporation (JP) 2011-11-23 EP disclosed
EP-2267083-A1 CURABLE COMPOSITION AND CURED MATERIAL Kaneka Corporation (JP) 2010-12-29 EP disclosed
EP-1988127-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2010-12-15 EP disclosed
EP-1985666-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2010-12-15 EP disclosed
US-20090182099-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2009-07-16 US disclosed
US-20090182091-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2009-07-16 US disclosed
EP-1988127-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-05 EP disclosed
EP-1985666-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product KDM2B, SETDB1, ASH2L ALDH1A1 615/4885F2 2662/4885F10 3114/4885
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT KDM2B, SETDB1, ASH2L ALDH1A1 615/4885F2 2662/4885F10 3114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.