Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PLTP | P55058 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403637 | 0.94 | TRPV4 (0.36) | TRPV4PI4KBMAPTPLTPLMNA | |
| SCHEMBL1008694 | 0.94 | TRPV4 (0.36) | TRPV4PI4KBMAPTPLTPLMNA | |
| SCHEMBL6700555 | 0.94 | TRPV4 (0.35) | TRPV4PI4KBMAPTALDH1A1HPGD | |
| SCHEMBL7688594 | 0.93 | TRPV4 (0.34) | TRPV4PI4KBMAPTPLTPLMNA | |
| SCHEMBL6703807 | 0.93 | PLTP (0.39) | TRPV4PI4KBMAPTALDH1A1PLTP | |
| SCHEMBL226080 | 0.93 | TRPV4 (0.32) | TRPV4PI4KBPLTPTP53 | |
| Water SCHEMBL7685985 | 0.93 | TRPV4 (0.33) | TRPV4PI4KBMAPTPLTPLMNA | |
| Trifluoroacetic Acid SCHEMBL226079 | 0.91 | TRPV4 (0.34) | TRPV4PI4KBMAPTALDH1A1PLTP | |
| Diethylamine SCHEMBL7031731 | 0.91 | TRPV4 (0.34) | TRPV4PI4KBMAPTALDH1A1PLTP | |
| Trifluoroacetic Acid SCHEMBL30480661 | 0.91 | TRPV4 (0.34) | TRPV4PI4KBMAPTALDH1A1PLTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |