Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701768 | 0.90 | POLB (0.50) | PARP15PARP10NPC1RAB9AHIF1A | |
| SCHEMBL6704355 | 0.81 | ACHE (0.44) | PARP15PARP10NPC1RAB9AMEN1 | |
| SCHEMBL1303034 | 0.81 | POLB (0.50) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL10917653 | 0.78 | NPC1 (0.51) | NPC1RAB9AHIF1AMEN1KMT2A | |
| SCHEMBL6702788 | 0.76 | ACHE (0.62) | PARP15PARP10NPC1RAB9AMEN1 | |
| SCHEMBL1922400 | 0.74 | NPC1 (0.57) | NPC1RAB9AHIF1AMEN1KMT2A | |
| SCHEMBL7688139 | 0.74 | NPC1 (0.67) | PARP15PARP10NPC1RAB9AMEN1 | |
| SCHEMBL8561688 | 0.73 | MEN1 (0.54) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL27914482 | 0.71 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL5996677 | 0.71 | MEN1 (0.51) | PARP15PARP10NPC1RAB9AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |