Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699183 | 0.90 | PARP15 (0.54) | POLBNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6704355 | 0.81 | ACHE (0.44) | POLBNPC1RAB9AMAPTHTT | |
| SCHEMBL6703810 | 0.81 | MAPT (0.48) | POLBRAB9AMAPTHTTNPSR1 | |
| SCHEMBL1303034 | 0.81 | POLB (0.50) | POLBNPC1RAB9AMAPTHTT | |
| SCHEMBL3362134 | 0.75 | MAPT (0.60) | POLBNPC1RAB9AMAPTHTT | |
| SCHEMBL5748247 | 0.74 | MAPT (0.58) | POLBRAB9AMAPTHTTNPSR1 | |
| SCHEMBL4113759 | 0.73 | MAPT (0.61) | RAB9AMAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL6477179 | 0.73 | METAP2 (0.60) | POLBNPC1RAB9A | |
| SCHEMBL13761323 | 0.71 | MAPT (0.62) | POLBRAB9AMAPTHTTNPSR1 | |
| SCHEMBL6983148 | 0.71 | ALDH1A1 (0.47) | RAB9AALDH1A1PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |