⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28423945 | 0.97 | TSHR (0.54) | — | |
| SCHEMBL28686448 | 0.79 | HDAC8 (0.62) | — | |
| SCHEMBL9508527 | 0.78 | TSHR (0.56) | — | |
| SCHEMBL13609165 | 0.76 | TSHR (0.54) | — | |
| SCHEMBL28696450 | 0.75 | CA2 (0.55) | — | |
| SCHEMBL8816540 | 0.74 | — | — | |
| SCHEMBL12864235 | 0.74 | — | — | |
| SCHEMBL6871426 | 0.74 | — | — | |
| SCHEMBL27118233 | 0.74 | USP2 (0.52) | — | |
| SCHEMBL28684278 | 0.74 | CA2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759553-B | Synthesis and application of water-soluble pyridazine derivative | 重庆大学 | 2022-10-04 | — | — | CN | claimed |
| CN-110668937-B | Method for preparing ester compound from amide | 徐州医科大学 | 2022-04-19 | — | — | CN | claimed |
| CN-114085218-A | Coumarin two-photon initiator and synthesis method and application thereof | 浙江大学 | 2022-02-25 | — | — | CN | claimed |
| CN-114058173-A | Process and composition for producing flexible polyurethane foams | 赢创运营有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-112759553-A | Synthesis and application of water-soluble pyridazine derivative | 重庆大学 | 2021-05-07 | — | — | CN | claimed |
| CN-112479913-A | Preparation method of N, N-diethyl chloroacetamide | 安徽修一制药有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-110668937-A | Method for preparing ester compound from amide | 徐州医科大学 | 2020-01-10 | — | — | CN | claimed |
| CN-101565839-B | Cyanogen to cyanogen-free alkali environment-friendly galvanizing brightener | WUHAN FENGFAN ELECTROPLATING TECHNOLOGY CO LTD | 2011-04-06 | — | — | CN | claimed |
| CN-101555609-B | An environment-protective alkali galvanization composition brightener for transformation from cyanide to non-cyanide | WUHAN FENGFAN ELECTROPLATING TECHNOLOGY CO LTD | 2010-08-04 | — | — | CN | claimed |
| CN-101565839-A | Cyanogen to cyanogen-free alkali environment-friendly galvanizing brightener | WUHAN FENGZHENG ELECTROPLATING (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-101555609-A | An environment-protective composition brightener for transformation between alkali non-cyanide galvanization and alkali cyanide galvanization | WUHAN FENGFAN ELECTROPLATING T (CN) | 2009-10-14 | — | — | CN | claimed |
| CN-114085218-B | Coumarin two-photon initiator and synthesis method and application thereof | 浙江大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-112898290-B | Isoxazole formamido-4 (3H) -quinazolinone derivative and synthesis method and application thereof | 中南大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114516840-A | Preparation method of 2- [ (6-chloropyridazin-3-yl) thio ] -N, N-diethylacetamide | 安徽修一制药有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-110668937-B | Method for preparing ester compound from amide | 徐州医科大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-1039809-A | The aminomethyl tetraline that replaces and the preparation of heterocycle homologue thereof | BAYER AG (DE) | 1990-02-21 | — | — | CN | disclosed |
| CN-1036566-A | 1,3,4,5-tetrahydro benzo [c, d] diindyl compounds | BAYER AG (DE) | 1989-10-25 | — | — | CN | disclosed |
| EP-0328251-A2 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-16 | — | — | EP | disclosed |
| CN-85106225-A | The preparation method of indole derivatives and the application in medical treatment thereof | — | 1987-02-18 | — | — | CN | disclosed |
| CN-85104426-A | Benzo [ 1 ] oxy [ 5 ] thiacycloheptene derivatives, their production and use | — | 1986-04-10 | — | — | CN | disclosed |