Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12790571 | 0.85 | HDAC8 (0.52) | TSHRUSP2CA1CA2CA12 | |
| SCHEMBL2058687 | 0.82 | CA2 (0.68) | TSHRUSP2CA1CA2KMT2A | |
| SCHEMBL13609165 | 0.81 | TSHR (0.54) | TSHRUSP2CA1CA2CA12 | |
| SCHEMBL8899976 | 0.81 | MMP1 (0.48) | TSHRUSP2CA1CA2CA12 | |
| SCHEMBL27118233 | 0.79 | USP2 (0.52) | TSHRUSP2CA1CA2CA12 | |
| SCHEMBL2314196 | 0.79 | MMP1 (0.46) | TSHRUSP2CA1CA2CA12 | |
| SCHEMBL30952371 | 0.79 | USP2 (0.47) | TSHRUSP2SMN1; SMN2LMNATDP1 | |
| SCHEMBL669950 | 0.78 | — | — | |
| SCHEMBL598066 | 0.77 | TSHR (0.50) | TSHRUSP2CA1CA2HTT | |
| SCHEMBL25634040 | 0.77 | KISS1R (0.51) | TSHRUSP2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214752-B2 | Homopolymers which exhibit a high level of photo-inducable birefringence | BAYER MATERIALSCIENCE AG (DE) | 2007-05-08 | — | — | US | disclosed |
| EP-0340706-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC-ACID CHLORIDES | BASF Aktiengesellschaft (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0340706-A2 | Process for the preparation of carboxylic-acid chlorides | BASF Aktiengesellschaft (DE) | 1989-11-08 | — | — | EP | disclosed |