Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658539 | 0.87 | HRH3 (0.51) | HRH4HRH3KDM4ECYP3A4MAPT | |
| SCHEMBL6660593 | 0.83 | HRH4 (0.42) | HRH4HRH3REN | |
| SCHEMBL6682337 | 0.81 | HRH4 (0.41) | HRH4HRH3REN | |
| SCHEMBL19210354 | 0.75 | TDP1 (0.55) | REN | |
| SCHEMBL7988978 | 0.73 | GBA1 (0.41) | HRH4HRH3RENCYSLTR1 | |
| SCHEMBL6682391 | 0.73 | HRH3 (0.47) | HRH4HRH3 | |
| SCHEMBL10355251 | 0.70 | CYP3A4 (0.58) | KDM4ECYP3A4MAPT | |
| SCHEMBL7624591 | 0.69 | GBA1 (0.47) | RENKDM4E | |
| Hydrochloric Acid SCHEMBL10355418 | 0.69 | KDM4E (0.56) | KDM4ECYP3A4MAPT | |
| SCHEMBL19210358 | 0.69 | TDP1 (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446385-A1 | PREPARATION AND USE OF SUBSTITUTED IMIDAZOLES | NOVO NORDISK A/S (DK) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003040106-A1 | PREPARATION AND USE OF SUBSTITUTED IMIDAZOLES | NOVO NORDISK A/S (DK) | 2003-05-15 | — | — | WO | disclosed |