Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 3/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | LCT | P09848 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697788 | 0.85 | HRH3 (0.56) | HRH3HRH4 | |
| SCHEMBL6682337 | 0.85 | HRH4 (0.41) | HRH3HRH4 | |
| SCHEMBL6658539 | 0.83 | HRH3 (0.51) | HRH3HRH4NAAAL3MBTL1TDP1 | |
| SCHEMBL6700085 | 0.73 | HRH4 (0.43) | HRH3HRH4 | |
| SCHEMBL6660593 | 0.70 | HRH4 (0.42) | HRH3HRH4TDP1 | |
| SCHEMBL6681815 | 0.69 | HRH3 (0.60) | HRH3HRH4TDP1 | |
| SCHEMBL9842913 | 0.68 | RXRA (0.49) | LSSFFAR1IDO1PPARGPPARD | |
| SCHEMBL27011138 | 0.66 | NAAA (0.58) | HRH3HRH4NAAAL3MBTL1TDP1 | |
| SCHEMBL6667210 | 0.66 | HRH3 (0.41) | HRH3HRH4TDP1IDO1 | |
| SCHEMBL21633701 | 0.65 | NAAA (0.58) | HRH3HRH4NAAAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446385-A1 | PREPARATION AND USE OF SUBSTITUTED IMIDAZOLES | NOVO NORDISK A/S (DK) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003040106-A1 | PREPARATION AND USE OF SUBSTITUTED IMIDAZOLES | NOVO NORDISK A/S (DK) | 2003-05-15 | — | — | WO | disclosed |