Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | REN | P00797 | 4/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210354 | 0.92 | TDP1 (0.55) | TDP1L3MBTL1CYP1A2BCHESIGMAR1 | |
| SCHEMBL16174483 | 0.82 | CYP1A2 (0.52) | TDP1CYP1A2SIGMAR1ALOX5SLC6A2 | |
| SCHEMBL6298407 | 0.80 | SIGMAR1 (0.58) | TDP1CYP1A2SIGMAR1TPSAB1SLC6A4 | |
| SCHEMBL4625658 | 0.80 | SIGMAR1 (0.58) | TDP1CYP1A2SIGMAR1TPSAB1SLC6A4 | |
| SCHEMBL20127257 | 0.80 | IDO1 (0.61) | TDP1L3MBTL1SIGMAR1IDO1HTR2A | |
| SCHEMBL6832302 | 0.79 | TDP1 (0.61) | TDP1L3MBTL1SIGMAR1IDO1 | |
| SCHEMBL22873138 | 0.79 | TDP1 (0.49) | TDP1L3MBTL1RENALOX5 | |
| SCHEMBL7648436 | 0.78 | TSHR (0.62) | CYP1A2RENALOX5SLC6A2HTR2A | |
| SCHEMBL2090154 | 0.76 | SIGMAR1 (0.50) | TDP1CYP1A2SIGMAR1TPSAB1SLC6A2 | |
| SCHEMBL29477161 | 0.76 | CYP1A2 (0.65) | CYP1A2BCHESIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205639-B1 | AGENT FOR INTRODUCING A PROTECTING GROUP FOR HYDROXY GROUP AND/OR FOR MERCAPTO GROUP | UNIV KYUSHU NAT UNIV CORP (JP) | 2021-08-11 | — | — | EP | disclosed |
| US-10160694-B2 | Agent for introducing protecting group for hydroxy group and/or mercapto group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-12-25 | — | — | US | disclosed |
| US-20170305809-A1 | AGENT FOR INTRODUCING PROTECTING GROUP FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| EP-3205639-A1 | PROTECTING-GROUP INTRODUCING AGENT FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | Kyushu University, National University Corporation (JP) | 2017-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160694-B2 | Agent for introducing protecting group for hydroxy group and/or mercapto group | GRHPR, AOX1, MSRB3 | TDP1 4306/4885L3MBTL1 1004/4885CYP1A2 262/4885 |
| US-20170305809-A1 | AGENT FOR INTRODUCING PROTECTING GROUP FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | GRHPR, AOX1, MSRB3 | TDP1 4306/4885L3MBTL1 1004/4885CYP1A2 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.