Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 11/20 | 0.57 |
| ▸ | DPP4 | P27487 | 7/20 | 0.46 |
| ▸ | FAP | Q12884 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699843 | 0.71 | HSD11B1 (0.55) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL5077374 | 0.70 | DPP4 (0.75) | PREPDPP4DPP8DPP7 | |
| SCHEMBL24447974 | 0.70 | PREP (0.82) | PREPDPP4DPP8DPP9 | |
| SCHEMBL7084540 | 0.69 | PREP (0.50) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL6704573 | 0.69 | DPP4 (0.55) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL6703269 | 0.67 | DPP4 (0.56) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL6703266 | 0.67 | DPP4 (0.56) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL1435982 | 0.67 | PREP (0.54) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL6335495 | 0.67 | PREP (0.48) | PREPDPP4 | |
| Oxalic Acid SCHEMBL6696017 | 0.67 | DPP4 (0.66) | PREPDPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | PREP 19/4885DPP4 1/4885FAP 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.