SCHEMBL6700624

SCHEMBL6700624

O=C1NS(=O)(=O)c2c1c(S(=O)(=O)O)c(S(=O)(=O)O)c(S(=O)(=O)O)c2S(=O)(=O)O

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.30
GRK5 P34947 1/20 0.30
TYRO3 Q06418 1/20 0.30
DYRK1B Q9Y463 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29185367 0.62 CA5A (0.46)
SCHEMBL6699520 0.61 CA12 (0.44) RETGRK5TYRO3DYRK1B
SCHEMBL9456175 0.52 LMNA (0.35)
SCHEMBL6512777 0.51 CA5A (0.31)
SCHEMBL3829783 0.51 DAPK1 (0.36)
SCHEMBL6513157 0.49 FABP3 (0.30)
SCHEMBL21403257 0.49 KDM4E (0.33)
SCHEMBL6522369 0.49 FABP3 (0.30)
SCHEMBL7917767 0.49 LMNA (0.36)
SCHEMBL16950309 0.49 DAPK1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040137082-A1 Compounds and methods for reducing myostatin concentration PHOENIX LABORATORIES INC 2004-07-15 US claimed
US-20040137083-A1 Method for making compounds for reducing myostatin concentration BIOTEST LABORATORIES 2004-07-15 US disclosed
US-20040137082-A1 Compounds and methods for reducing myostatin concentration PHOENIX LABORATORIES INC 2004-07-15 US disclosed