Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428044 | 0.80 | CA1 (0.41) | STAT3CA2CA9CA12CA1 | |
| SCHEMBL6700703 | 0.79 | CA2 (0.40) | STAT3CA2CA9CA12CA1 | |
| SCHEMBL6111191 | 0.73 | CA2 (0.46) | STAT3CA2CA9CA12CA1 | |
| SCHEMBL2170005 | 0.71 | CA2 (0.42) | STAT3CA2CA9CA12CA1 | |
| SCHEMBL30340124 | 0.70 | CYP2A6 (0.47) | EDNRAPTPRCMEN1KMT2AUSP2 | |
| SCHEMBL12819940 | 0.70 | CYP2A6 (0.47) | EDNRAPTPRCMEN1KMT2AUSP2 | |
| SCHEMBL4788421 | 0.70 | CA2 (0.55) | STAT3CA2CA9CA12CA1 | |
| SCHEMBL9108195 | 0.70 | CA2 (0.55) | STAT3CA2CA9CA12CA1 | |
| SCHEMBL27200808 | 0.69 | PRMT6 (0.48) | EDNRACA2CA1PTPRC | |
| SCHEMBL6111776 | 0.69 | SCN9A (0.42) | CA2CA9CA12CA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112779-A1 | NEW USE VII | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | claimed |