Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.69 |
| ▸ | MAOB | P27338 | 11/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
| ▸ | STS | P08842 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536102 | 0.92 | AR (0.63) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL6700953 | 0.88 | MAOB (0.69) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL6699546 | 0.84 | AR (0.73) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL11242828 | 0.84 | AR (0.70) | ARMAOBCYP19A1KDM4EHSD17B10 | |
| SCHEMBL10534793 | 0.84 | AR (0.50) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL11049080 | 0.83 | MAOB (0.79) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL11049084 | 0.83 | MAOB (0.79) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL13965321 | 0.83 | MAOB (0.50) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL10362227 | 0.82 | AR (1.00) | ARMAOBCYP19A1ADORA3KDM4E | |
| SCHEMBL14053522 | 0.82 | AR (0.74) | ARMAOBCYP19A1ADORA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | ADVANCED LIFE SCIENCES, INC. | 2004-07-29 | — | — | US | disclosed |
| US-6677350-B1 | ADMINISTERING CHALCONE-LIKE VINYLCARBONYL COMPOUNDS TO PREVENT OR TREAT MYCOBACTERIUM INFECTIONS/TUBERCULOSIS | ADVANCED LIFE SCIENCES, INC. | 2004-01-13 | — | — | US | disclosed |
| US-4874869-A | TREATMENT OF DIABETIC COMPLICATIONS, CATARACTS | EISAI CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
| US-4461907-A | Amino-substituted flavans useful as anti-viral agents | BURROUGHS WELLCOME CO. | 1984-07-24 | — | — | US | disclosed |
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | disclosed |
| EP-0051061-A2 | Novel intermediates and process for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-05-05 | — | — | EP | disclosed |
| EP-0004579-A1 | Flavans, process for their preparation and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | IMMT, CYP51A1, LSS | AR 3497/4885MAOB 1715/4885CYP19A1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.