Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12932913 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL6698866 | 0.81 | MAPT (0.54) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL13846824 | 0.80 | MEN1 (0.40) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL10852321 | 0.79 | SLC6A2 (0.50) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14397073 | 0.79 | CA1 (0.46) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL8613449 | 0.79 | KMT2A (0.42) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL6702352 | 0.78 | TAAR1 (0.46) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL7945715 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL6698887 | 0.76 | GAA (0.59) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6702634 | 0.76 | MEN1 (0.47) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968580-B2 | Imidazolidin-2-one derivatives as selective androgen receptor modulators (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2011-06-28 | — | — | US | disclosed |
| US-20090215848-A1 | Novel imidazolidIn-2-one derivatives as selective androgen receptor modulators (SARMS) | LANTER JAMES C | 2009-08-27 | — | — | US | disclosed |
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215848-A1 | Novel imidazolidIn-2-one derivatives as selective androgen receptor modulators (SARMS) | AR, NR5A1, NR5A2 | KIT 921/4885PIM1 1428/4885FLT3 2200/4885 |
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | KIT 2168/4885PIM1 2790/4885FLT3 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.