Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1565673 | 0.98 | ALDH1A1 (0.42) | ALDH1A1ALOX12SMN1; SMN2KDM4EGAA | |
| SCHEMBL146034 | 0.86 | IDO1 (0.45) | ALDH1A1SMN1; SMN2GAAALOX15HSD17B10 | |
| SCHEMBL8611549 | 0.81 | NPC1 (0.46) | ALDH1A1SMN1; SMN2KDM4EGAACA1 | |
| SCHEMBL22414272 | 0.80 | MAPT (0.37) | ALDH1A1SMN1; SMN2CA1CA2CA12 | |
| Ammonia Solution, Strong SCHEMBL6698868 | 0.80 | MAPT (0.56) | ALDH1A1SMN1; SMN2KDM4EGAAHPGD | |
| SCHEMBL23504460 | 0.79 | CA1 (0.39) | SMN1; SMN2KDM4ECA1CA2CA12 | |
| SCHEMBL26000374 | 0.78 | MEN1 (0.47) | ALOX12SMN1; SMN2KDM4EGAAHPGD | |
| SCHEMBL25095026 | 0.77 | TSHR (0.40) | ALDH1A1SMN1; SMN2HPGDALOX15HSD17B10 | |
| SCHEMBL7794063 | 0.77 | MAPT (0.58) | ALDH1A1SMN1; SMN2KDM4EGAAHPGD | |
| Ammonia Solution, Strong SCHEMBL6702357 | 0.77 | MAPT (0.50) | ALDH1A1ALOX12SMN1; SMN2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | ALDH1A1 925/4885ALOX12 3909/4885SMN1; SMN2 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.