Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14081111 | 0.83 | IDO1 (0.43) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL1565673 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL13057582 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL22622594 | 0.81 | MAPT (0.54) | NPC1RAB9AMEN1KMT2AGAA | |
| Ammonia Solution, Strong SCHEMBL6701042 | 0.81 | ALDH1A1 (0.44) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL5713045 | 0.81 | MAPT (0.54) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL18457999 | 0.80 | KIF11 (0.46) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL18457684 | 0.80 | KIF11 (0.46) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL33958 | 0.79 | CA12 (0.40) | RAB9ACA12CA1CA2CA9 | |
| SCHEMBL11342357 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2AGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | disclosed |
| EP-0648758-A1 | 4-Arylamino-benzopyran and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |