Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671244 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12077838 | 0.77 | MAPT (0.73) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2569729 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL26931067 | 0.75 | ALDH1A1 (0.61) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17645850 | 0.75 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6697256 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29977958 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4804914 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1256644 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30693037 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | SMN1; SMN2 3810/4885MAPT 3376/4885ALDH1A1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.