Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 5/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701378 | 0.86 | PPM1D (0.36) | ACKR3SAE1UBA2ROCK2KMT2A | |
| SCHEMBL6700553 | 0.85 | CHRM4 (0.33) | SAE1UBA2ROCK2KMT2AMAPT | |
| SCHEMBL6701383 | 0.84 | SAE1 (0.34) | SAE1UBA2ROCK2KMT2APOLB | |
| SCHEMBL6703576 | 0.80 | MAPT (0.36) | ACKR3SAE1UBA2MAPTTRPV4 | |
| SCHEMBL27581687 | 0.80 | PPM1D (0.36) | ACKR3ROCK2MAPTTRPV4SMN1; SMN2 | |
| SCHEMBL6702286 | 0.80 | MAPT (0.32) | SAE1ROCK2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6704409 | 0.80 | MAPT (0.32) | SAE1ROCK2KMT2AMAPTTRPV4 | |
| SCHEMBL7686588 | 0.80 | F10 (0.36) | KMT2AMAPTSMN1; SMN2THRBKDM4E | |
| SCHEMBL6703562 | 0.79 | MAPT (0.33) | KMT2AMAPTTRPV4SMN1; SMN2KDM4E | |
| SCHEMBL6703026 | 0.79 | MAPT (0.34) | KMT2AMAPTTRPV4SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |