Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PPM1D | O15297 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | PLTP | P55058 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TPH1 | P17752 | 2/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701378 | 0.94 | PPM1D (0.36) | MAPTPPM1DTRPV4PLTPTP53 | |
| SCHEMBL27581687 | 0.91 | PPM1D (0.36) | MAPTPPM1DTRPV4PLTPTPH1 | |
| SCHEMBL6703028 | 0.86 | TRPV4 (0.36) | MAPTTRPV4SCDPLTPTP53 | |
| SCHEMBL6703565 | 0.86 | TRPV4 (0.35) | MAPTTRPV4SCDPLTPTP53 | |
| SCHEMBL7092957 | 0.86 | TRPV4 (0.36) | MAPTTRPV4PLTPTP53SMN1; SMN2 | |
| SCHEMBL6701383 | 0.81 | SAE1 (0.34) | MAPTTRPV4TPH1TPH2THRB | |
| SCHEMBL6701375 | 0.80 | ACKR3 (0.36) | MAPTTRPV4THRBSMN1; SMN2ACKR3 | |
| SCHEMBL27598406 | 0.79 | PLTP (0.41) | MAPTTRPV4PLTPTP53SMN1; SMN2 | |
| SCHEMBL6700555 | 0.79 | TRPV4 (0.35) | MAPTTRPV4PLTPSMN1; SMN2SAE1 | |
| SCHEMBL6698972 | 0.78 | TRPV4 (0.34) | MAPTTRPV4PLTPTP53SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |