Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PLTP | P55058 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703576 | 0.94 | MAPT (0.36) | PPM1DTRPV4SAE1UBA2ACKR3 | |
| SCHEMBL27581687 | 0.93 | PPM1D (0.36) | PPM1DTRPV4ACKR3MAPTPLTP | |
| SCHEMBL7092957 | 0.88 | TRPV4 (0.36) | TRPV4KMT2APOLBMAPTPLTP | |
| SCHEMBL6701383 | 0.88 | SAE1 (0.34) | TRPV4SAE1UBA2KMT2APOLB | |
| SCHEMBL6701375 | 0.86 | ACKR3 (0.36) | TRPV4SAE1UBA2ACKR3KMT2A | |
| SCHEMBL6700555 | 0.85 | TRPV4 (0.35) | TRPV4SAE1UBA2KMT2AMAPT | |
| SCHEMBL27598406 | 0.81 | PLTP (0.41) | TRPV4KMT2APOLBMAPTPLTP | |
| SCHEMBL1008694 | 0.80 | TRPV4 (0.36) | TRPV4SAE1KMT2AMAPTPLTP | |
| SCHEMBL6698972 | 0.80 | TRPV4 (0.34) | TRPV4SAE1MAPTPLTPALDH1A1 | |
| SCHEMBL7686591 | 0.79 | TRPV4 (0.36) | TRPV4KMT2AMAPTPLTPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |