Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705567 | 0.97 | ALDH1A1 (0.47) | HPGDALDH1A1USP2MC4RHTT | |
| SCHEMBL6704676 | 0.91 | TP53 (0.46) | ALDH1A1LMNAPTGESHSD17B10CACNA1G | |
| SCHEMBL6701163 | 0.76 | LMNA (0.40) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6699001 | 0.75 | LMNA (0.46) | HPGDALDH1A1HTTLMNATSHR | |
| SCHEMBL5428707 | 0.71 | HPGD (0.48) | HPGDALDH1A1USP2MC4RHTT | |
| SCHEMBL29221193 | 0.67 | APEX1 (0.44) | HPGDHTTLMNATSHRKMT2A | |
| SCHEMBL29941835 | 0.66 | HPGD (0.66) | HPGDALDH1A1USP2MC4RHTT | |
| SCHEMBL8998862 | 0.66 | HPGD (0.66) | HPGDALDH1A1USP2MC4RHTT | |
| SCHEMBL16446870 | 0.66 | HPGD (0.57) | HPGDALDH1A1USP2MC4RHTT | |
| SCHEMBL16446872 | 0.66 | HPGD (0.57) | HPGDALDH1A1USP2MC4RHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MORPHOCHEM AG (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MAP3K20, MAP3K21, MAP3K1 | HPGD 981/4885ALDH1A1 2905/4885USP2 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.