O-Tolylamine

O-Tolylamine

SCHEMBL6701427

Cc1ccccc1N.NCC1CO1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
CYP3A4 P08684 1/20 0.56
ALDH1A1 P00352 1/20 0.44
GLA P06280 1/20 0.44
HTR2A P28223 2/20 0.43
HTR2C P28335 2/20 0.43
HTR2B P41595 2/20 0.43
CD44 P16070 1/20 0.39
TAAR1 Q96RJ0 2/20 0.38
SLC6A2 P23975 6/20 0.37
SLC6A4 P31645 4/20 0.37
SLC6A3 Q01959 2/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
CYP2D6 P10635 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Questiomycin B SCHEMBL3614014 0.79 ALOX15 (0.56) TDP1CYP3A4ALDH1A1GLAHTR2A
O-Tolylamine SCHEMBL29441724 0.76
O-Tolylamine SCHEMBL15789 0.76
O-Tolylamine SCHEMBL9613766 0.76 CYP3A4 (0.94) TDP1CYP3A4ALDH1A1CD44
O-Tolylamine SCHEMBL8469060 0.76 CYP3A4 (0.94) TDP1CYP3A4ALDH1A1CD44
O-Tolylamine SCHEMBL31145800 0.76
Biphenyl SCHEMBL23781834 0.75 SLC6A2 (0.46) TDP1ALDH1A1TAAR1SLC6A2SLC6A4
O-Tolylamine SCHEMBL11231934 0.73 CYP3A4 (0.88) TDP1CYP3A4ALDH1A1CD44
O-Tolylamine SCHEMBL21494153 0.73
O-Tolylamine SCHEMBL22471782 0.73 CYP3A4 (0.88) TDP1CYP3A4ALDH1A1CD44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004010878-A LIQUID EPOXY RESIN, EPOXY RESIN COMPOSITION AND ITS CURED PRODUCT NIPPON KAYAKU CO LTD 2004-01-15 JP disclosed