Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR1F | P30939 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449326 | 0.94 | MCL1 (0.63) | KDM4EALDH1A1MCL1FOLH1HTR6 | |
| SCHEMBL2204353 | 0.90 | HTR6 (0.74) | KDM4EALDH1A1MCL1HTR6HTR1A | |
| SCHEMBL3107169 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1MCL1FOLH1HTR6 | |
| SCHEMBL20037062 | 0.85 | ALDH1A1 (0.59) | KDM4EALDH1A1HTR6HTR1ADRD2 | |
| SCHEMBL9011379 | 0.83 | HTR6 (0.54) | KDM4EALDH1A1MCL1HTR6HTR1A | |
| SCHEMBL9188195 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1MCL1FOLH1 | |
| SCHEMBL29432490 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1MCL1FOLH1 | |
| SCHEMBL3881052 | 0.81 | MCL1 (0.67) | KDM4EALDH1A1MCL1FOLH1HPGD | |
| SCHEMBL3276610 | 0.79 | KDM4E (0.83) | KDM4EALDH1A1MCL1FOLH1BCL2 | |
| SCHEMBL29368058 | 0.79 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |