Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700774 | 0.81 | HPGD (0.46) | HPGDALOX15KMT2AMAPTALDH1A1 | |
| SCHEMBL6700580 | 0.79 | HPGD (0.44) | HPGDALOX15KMT2AMAPTALDH1A1 | |
| SCHEMBL6703334 | 0.79 | PPARG (0.38) | ALOX15KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL6704728 | 0.75 | EPHX1 (0.48) | HPGDKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL6703375 | 0.74 | TP53 (0.43) | HPGDKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL27792176 | 0.70 | HTT (0.65) | HPGDALOX15NCEH1L3MBTL1TSHR | |
| SCHEMBL3750037 | 0.66 | KCNA5 (0.56) | ALDH1A1GAA | |
| SCHEMBL30553831 | 0.66 | HPGD (0.51) | HPGDALOX15NCEH1CYP1A2CYP3A4 | |
| SCHEMBL20772779 | 0.66 | HPGD (0.51) | HPGDALOX15NCEH1CYP1A2CYP3A4 | |
| SCHEMBL1093718 | 0.66 | TSHR (0.73) | HPGDKMT2AMEN1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MORPHOCHEM AG (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MAP3K20, MAP3K21, MAP3K1 | HPGD 981/4885ALOX15 1518/4885KMT2A 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.