Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703580 | 0.80 | GAA (0.49) | EPHX1EPHX2TSHRKDM4EALDH1A1 | |
| SCHEMBL6704475 | 0.78 | LMNA (0.49) | EPHX1EPHX2KDM4EALDH1A1RAB9A | |
| SCHEMBL6701630 | 0.75 | HPGD (0.41) | EPHX1TSHRKDM4EALDH1A1MEN1 | |
| SCHEMBL6704655 | 0.73 | NPC1 (0.49) | EPHX1EPHX2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3456146 | 0.67 | NPC1 (0.65) | EPHX1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3954720 | 0.67 | NPC1 (0.65) | EPHX1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30073645 | 0.67 | NPC1 (0.65) | EPHX1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2751444 | 0.66 | DRD4 (0.64) | EPHX1KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL2752183 | 0.65 | EPHX1 (0.67) | EPHX1EPHX2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10089305 | 0.65 | EPHX1 (1.00) | EPHX1TSHRKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MORPHOCHEM AG (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MAP3K20, MAP3K21, MAP3K1 | EPHX1 1620/4885EPHX2 2313/4885TSHR 4168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.