SCHEMBL6701743

SCHEMBL6701743

COCCc1nc2c(c3ccccc3n3nnnc23)n1CCOCCCc1cccnc1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 12/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ADORA2B P29275 1/20 0.33
HRH1 P35367 1/20 0.33
HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6696022 0.88 ALDH1A1 (0.38) TLR7ALDH1A1GAAHTTNPSR1
SCHEMBL6704175 0.80 KDM4E (0.36) SMN1; SMN2ALDH1A1GAAHRH1HTR6
SCHEMBL6702935 0.79 TLR7 (0.61) TLR7
SCHEMBL6700118 0.71 TLR7 (0.74) TLR7
SCHEMBL7107891 0.70 KDM4E (0.36) SMN1; SMN2ALDH1A1GAAHTTNPSR1
SCHEMBL6106117 0.70 TLR7 (0.63) TLR7
SCHEMBL7106797 0.67 HPGD (0.40) SMN1; SMN2ALDH1A1GAAHTTNPSR1
SCHEMBL6105787 0.67 SMN1; SMN2 (0.45) TLR7SMN1; SMN2ALDH1A1GAA
SCHEMBL27581442 0.67 CYP3A4 (0.43) HRH1
SCHEMBL483652 0.66 TLR7 (0.57) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040072858-A1 Heterocyclic ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2004-04-15 US disclosed
US-6664260-B2 Viricides; anticarcinogneic agents; induction cytokine biosynthesis 3M INNOVATIVE PROPERTIES COMPANY 2003-12-16 US disclosed
EP-1339715-A2 HETEROCYCLIC ETHER SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2003-09-03 EP disclosed
US-20030065005-A1 Heterocyclic ether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2003-04-03 US disclosed
WO-2002046193-A2 HETEROCYCLIC ETHER SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065005-A1 Heterocyclic ether substituted imidazoquinolines IFNG, IL2, IRF3 TLR7 35/4885SMN1; SMN2 4312/4885ALDH1A1 2486/4885
US-20040072858-A1 Heterocyclic ether substituted imidazoquinolines IFNG, IL2, IRF3 TLR7 35/4885SMN1; SMN2 4312/4885ALDH1A1 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.