Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25225286 | 0.89 | — | — | |
| SCHEMBL6704692 | 0.81 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL11436132 | 0.78 | TSHR (0.46) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL20173448 | 0.78 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL3699223 | 0.76 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL8895107 | 0.75 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL776553 | 0.74 | GBA1 (0.44) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL11466905 | 0.72 | CES2 (0.38) | ALDH1A1TSHR | |
| SCHEMBL7686193 | 0.72 | ALDH1A1 (0.40) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL1808486 | 0.71 | TSHR (0.42) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| CN-1478075-A | Chemical process and new intermediates | ��ŵ�Ѻϳ�ʵ���� | 2004-02-25 | — | — | CN | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |