SCHEMBL670197

SCHEMBL670197

c1ccc(/N=N/c2cccnc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
TRPA1 O75762 2/20 0.55
MAPT P10636 5/20 0.53
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
TDP1 Q9NUW8 2/20 0.53
HTR3E A5X5Y0 1/20 0.52
HTR3B O95264 1/20 0.52
HTR3A P46098 1/20 0.52
HTR3D Q70Z44 1/20 0.52
HTR3C Q8WXA8 1/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
MITF O75030 1/20 0.48
CFTR P13569 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL670198 1.00 ALDH1A1 (0.57) ALDH1A1TRPA1MAPTMEN1KMT2A
SCHEMBL5174355 0.93 HTR3E (0.58) ALDH1A1TRPA1MAPTMEN1KMT2A
SCHEMBL3284038 0.93 HTR3E (0.58) ALDH1A1TRPA1MAPTMEN1KMT2A
SCHEMBL32679882 0.83 MEN1 (0.59) ALDH1A1TRPA1MAPTMEN1KMT2A
SCHEMBL148825 0.83 HTR3E (0.46) ALDH1A1TRPA1MAPTMEN1KMT2A
SCHEMBL148824 0.83 HTR3E (0.46) ALDH1A1TRPA1MAPTMEN1KMT2A
SCHEMBL12669320 0.83 MEN1 (0.59) ALDH1A1TRPA1MAPTMEN1KMT2A
Azobenzene SCHEMBL29193155 0.82 ALDH1A1 (0.67) ALDH1A1TRPA1MAPTMEN1KMT2A
SCHEMBL9186168 0.81 HTR3E (0.52) ALDH1A1TRPA1MAPTMEN1KMT2A
Azobenzene SCHEMBL28277084 0.80 ALDH1A1 (0.63) ALDH1A1TRPA1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2605774-B1 MOLECULAR SWITCH UNIV KIEL CHRISTIAN ALBRECHTS (DE) 2018-11-14 EP disclosed
US-9786420-B2 Molecular switch CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) 2017-10-10 US disclosed
US-9404001-B2 Photochromic latex ink XEROX CORPORATION (US) 2016-08-02 US disclosed
US-20150153479-A1 PHOTOCHROMIC LATEX INK XEROX CORPORATION (US) 2015-06-04 US disclosed
US-20130202538-A1 Molecular Switch UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN (DE) 2013-08-08 US disclosed
EP-2605774-A1 MOLECULAR SWITCH Christian-Albrechts-Universität zu Kiel (DE) 2013-06-26 EP disclosed
WO-2012022299-A1 MOLECULAR SWITCH CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) 2012-02-23 WO disclosed
US-7708396-B2 Photochromic phase change inks XEROX CORPORATION (US) 2010-05-04 US disclosed
US-20070211124-A1 PHOTOCHROMIC PHASE CHANGE INKS XEROX CORPORATION (US) 2007-09-13 US disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed