Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337933 | 0.76 | TRPA1 (0.56) | — | |
| SCHEMBL6603131 | 0.76 | TRPA1 (0.56) | — | |
| SCHEMBL134931 | 0.72 | CYP1A2 (0.34) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL1666091 | 0.71 | PDE3B (0.38) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL30804579 | 0.69 | TRPA1 (0.59) | CYP2A6CYP1A2 | |
| SCHEMBL1119424 | 0.69 | TRPA1 (0.59) | CYP2A6CYP1A2 | |
| SCHEMBL15388979 | 0.69 | LMNA (0.46) | TDP1GAATSHR | |
| SCHEMBL2512609 | 0.69 | TRPA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4046012 | 0.69 | PDE3B (0.37) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL3459194 | 0.68 | NPC1 (0.39) | MEN1KMT2ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263934-A | Preparation method of 5H-benzo [ c ] [1,6] naphthyridine-6-ketone derivative | 上海凌凯医药科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| EP-2847168-A1 | ANTIBACTERIAL AGENTS | Achaogen, Inc. (US) | 2015-03-18 | — | — | EP | claimed |
| WO-2013170165-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2013-11-14 | — | — | WO | claimed |
| WO-2012015875-A1 | METHODS FOR TREATING HEMATOLOGICAL MALIGNANCIES | GENZYME CORPORATION (US) | 2012-02-02 | — | — | WO | claimed |
| WO-2009114459-A2 | ANTI-NEOPLASTIC COMBINATION THERAPEUTIC REGIMEN INVOLVING CO-DISRUPTION OF PARP PATHWAY AND MRE11/RAD50/NBS1 COMPLEX AND COMPOSITONS USEFUL THEREIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-09-17 | — | — | WO | claimed |
| EP-1751157-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC. (US) | 2007-02-14 | — | — | EP | claimed |
| WO-2005103051-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC. (US) | 2005-11-03 | — | — | WO | claimed |
| EP-4727647-A1 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259178-A1 | GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-119119296-A | Allogeneic cell compositions and methods of use | 波赛达治疗公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118878697-A | VCAR compositions and methods of use | 波赛达治疗公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-113383018-B | Allogeneic cell compositions and methods of use | 波赛达治疗公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114901626-B | Photo-induced catalytic C-H oxidation of alkanes | 阿里尔科技创新公司 | 2024-07-19 | — | — | CN | disclosed |
| EP-1934220-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | Pfizer Products Incorporated (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2008010964-A1 | 1-HYDROXY NAPHTHYRIDINE COMPOUNDS AS ANTI-HIV AGENTS | MERCK & CO., INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007042883-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER PRODUCTS INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| EP-1751157-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005103051-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC. (US) | 2005-11-03 | — | — | WO | disclosed |
| CN-1675207-A | 6-alkoxy-pyrido-pyrimidines as p-38 MAP kinase inhibitors | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | CN | disclosed |
| EP-0000490-A1 | Substituted naphthyridinones, processes for their preparations and therapeutical applications | MERCK & CO. INC. (US) | 1979-02-07 | — | — | EP | disclosed |