SCHEMBL670229

SCHEMBL670229

O=C(O)C=CCC1=CC(=O)NC1=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.33
GABRR2 P28476 2/20 0.33
BLM P54132 2/20 0.33
GABRR3 A8MPY1 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
APEX1 P27695 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTGER4 P35408 1/20 0.31
PTGER3 P43115 1/20 0.31
PTGER2 P43116 1/20 0.31
PLA2G10 O15496 1/20 0.31
PLA2G5 P39877 1/20 0.31
HCAR2 Q8TDS4 2/20 0.31
HDAC3 O15379 1/20 0.31
TNKS O95271 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4591048 0.79
SCHEMBL18296915 0.78
SCHEMBL8989659 0.76
SCHEMBL4973319 0.76
SCHEMBL6537078 0.76
SCHEMBL6537082 0.76
SCHEMBL18296899 0.74 ALDH1A1 (0.31) TSHR
SCHEMBL327468 0.71
SCHEMBL4008196 0.71 GABRR1 (0.33) GABRR1GABRR2LMNATSHR
SCHEMBL3162544 0.68 KEAP1 (0.38) LMNANPSR1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9850373-B2 Curable polymer mixture BYK-CHEMIE, GMBH (DE) 2017-12-26 US disclosed
EP-2606074-B1 CURABLE POLYMER MIXTURE BYK CHEMIE GMBH (DE) 2014-07-23 EP disclosed
US-20130289195-A1 Curable Polymer Mixture BYK-CHEMIE GMBH (DE) 2013-10-31 US disclosed
EP-2606074-A1 CURABLE POLYMER MIXTURE BYK-Chemie GmbH (DE) 2013-06-26 EP disclosed
WO-2012022436-A1 CURABLE POLYMER MIXTURE BYK-CHEMIE GMBH (DE) 2012-02-23 WO disclosed