Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684379 | 0.89 | SIGMAR1 (0.41) | SIGMAR1KMT2AL3MBTL1SYKGPBAR1 | |
| SCHEMBL6697720 | 0.89 | SIGMAR1 (0.41) | SIGMAR1KMT2AL3MBTL1SYKGPBAR1 | |
| SCHEMBL6697681 | 0.89 | SIGMAR1 (0.41) | SIGMAR1KMT2AL3MBTL1SYKGPBAR1 | |
| SCHEMBL6697249 | 0.86 | SIGMAR1 (0.39) | SIGMAR1KMT2AL3MBTL1SYKCTSL | |
| SCHEMBL6697678 | 0.83 | SIGMAR1 (0.43) | SIGMAR1KMT2AL3MBTL1SYKCTSL | |
| SCHEMBL6702372 | 0.82 | SIGMAR1 (0.43) | SIGMAR1KMT2AL3MBTL1SYKCTSL | |
| SCHEMBL6697716 | 0.81 | SIGMAR1 (0.42) | SIGMAR1KMT2AL3MBTL1CTSLCTSB | |
| SCHEMBL7684372 | 0.81 | SIGMAR1 (0.42) | SIGMAR1KMT2AL3MBTL1CTSLCTSB | |
| SCHEMBL6697877 | 0.81 | SIGMAR1 (0.46) | SIGMAR1KMT2AL3MBTL1CTSLCHRM5 | |
| SCHEMBL6695382 | 0.80 | SIGMAR1 (0.45) | SIGMAR1KMT2AL3MBTL1GPBAR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097471-A1 | Inhibitors of neuraminidases | ABBVIE INC. | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097471-A1 | Inhibitors of neuraminidases | NEU1, NEU2, NEU4 | SIGMAR1 3896/4885KMT2A 3372/4885L3MBTL1 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.