Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697716 | 1.00 | SIGMAR1 (0.42) | SIGMAR1CTSKKMT2ACTSLL3MBTL1 | |
| SCHEMBL7027500 | 0.91 | SIGMAR1 (0.45) | SIGMAR1CTSKCTSLCTSBCTSS | |
| SCHEMBL6697245 | 0.86 | SIGMAR1 (0.40) | SIGMAR1CTSKKMT2ACTSLL3MBTL1 | |
| SCHEMBL6702372 | 0.85 | SIGMAR1 (0.43) | SIGMAR1CTSKKMT2ACTSLL3MBTL1 | |
| SCHEMBL6697678 | 0.82 | SIGMAR1 (0.43) | SIGMAR1CTSKKMT2ACTSLL3MBTL1 | |
| SCHEMBL6702380 | 0.81 | SIGMAR1 (0.43) | SIGMAR1CTSKKMT2ACTSLL3MBTL1 | |
| SCHEMBL6697877 | 0.80 | SIGMAR1 (0.46) | SIGMAR1KMT2ACTSLL3MBTL1ALDH1A1 | |
| SCHEMBL7684379 | 0.79 | SIGMAR1 (0.41) | SIGMAR1KMT2ACTSLL3MBTL1ADORA3 | |
| SCHEMBL6697720 | 0.79 | SIGMAR1 (0.41) | SIGMAR1KMT2ACTSLL3MBTL1ADORA3 | |
| SCHEMBL6695382 | 0.79 | SIGMAR1 (0.45) | SIGMAR1KMT2ACTSLL3MBTL1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455571-B1 | ESPECIALLY, INFLUENZA NEURAMINIDASE. | ABBOTT LABORATORIES | 2002-09-24 | — | — | US | disclosed |