Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671123 | 0.74 | TSHR (0.42) | TSHRMAPK1 | |
| SCHEMBL4969152 | 0.69 | TSHR (0.70) | TSHRTHRBMAPK1 | |
| SCHEMBL11857799 | 0.68 | THRB (0.37) | TSHRTHRB | |
| SCHEMBL6339685 | 0.66 | TSHR (0.74) | TSHRTHRB | |
| Di(Hydroxyethyl)Ether SCHEMBL27625390 | 0.66 | TSHR (0.80) | TSHRTHRB | |
| SCHEMBL5454703 | 0.66 | TSHR (0.79) | TSHRTHRB | |
| SCHEMBL19077763 | 0.66 | TSHR (0.79) | TSHRTHRB | |
| SCHEMBL2997982 | 0.66 | TSHR (0.79) | TSHRTHRB | |
| SCHEMBL5455892 | 0.66 | TSHR (0.79) | TSHRTHRB | |
| SCHEMBL7198622 | 0.66 | TSHR (0.86) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024688-A1 | MULTIPHASE SYSTEMS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | claimed |
| WO-2012024688-A1 | MULTIPHASE SYSTEMS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |