Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702441 | 0.94 | MAPT (0.39) | GAATRPV4MAPTTP53DYRK1A | |
| SCHEMBL7686591 | 0.94 | TRPV4 (0.36) | GAATRPV4MAPTTP53ALDH1A1 | |
| SCHEMBL7684176 | 0.93 | TRPV4 (0.38) | GAATRPV4MAPTTP53DYRK1A | |
| SCHEMBL7684903 | 0.92 | KMT2A (0.42) | GAATRPV4MEN1KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL7682405 | 0.91 | ATM (0.35) | GAATRPV4MAPTTP53ALDH1A1 | |
| SCHEMBL7679779 | 0.88 | TRPV4 (0.37) | GAATRPV4MEN1KMT2APOLB | |
| SCHEMBL6703653 | 0.87 | MEN1 (0.37) | TRPV4MAPTTP53ALDH1A1HPGD | |
| SCHEMBL7684406 | 0.87 | MAPT (0.34) | TRPV4MAPTTP53ALDH1A1HPGD | |
| SCHEMBL6702802 | 0.86 | GAA (0.39) | GAATRPV4MAPTTP53DYRK1A | |
| SCHEMBL7679752 | 0.86 | MEN1 (0.38) | TRPV4MAPTTP53SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |