Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | PLTP | P55058 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682217 | 0.94 | TRPV4 (0.38) | KMT2AMEN1CCKARTRPV4GAA | |
| SCHEMBL7677660 | 0.93 | TRPV4 (0.37) | KMT2AMEN1CCKARTRPV4GAA | |
| SCHEMBL7688740 | 0.92 | MEN1 (0.46) | KMT2AMEN1CCKARTRPV4ECE1 | |
| SCHEMBL7686591 | 0.92 | TRPV4 (0.36) | KMT2AMEN1CCKARTRPV4GAA | |
| SCHEMBL7682301 | 0.92 | TRPV4 (0.40) | KMT2AMEN1CCKARTRPV4GAA | |
| SCHEMBL6702797 | 0.92 | GAA (0.39) | KMT2AMEN1TRPV4GAAECE1 | |
| SCHEMBL7679779 | 0.92 | TRPV4 (0.37) | KMT2AMEN1CCKARTRPV4GAA | |
| Trifluoroacetic Acid SCHEMBL7682405 | 0.89 | ATM (0.35) | KMT2AMEN1CCKARTRPV4GAA | |
| SCHEMBL7688378 | 0.87 | MEN1 (0.38) | KMT2AMEN1CCKARTRPV4GAA | |
| SCHEMBL7679717 | 0.87 | MEN1 (0.40) | KMT2AMEN1CCKARTRPV4ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |