Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27973589 | 0.82 | TSHR (0.44) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11405289 | 0.78 | MEN1 (0.43) | MAPTHTTNPSR1MEN1KMT2A | |
| SCHEMBL11405195 | 0.78 | MAPT (0.57) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11296546 | 0.78 | CYP1A2 (0.57) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6312344 | 0.77 | MEN1 (0.47) | MAPTHTTCYP3A4NPSR1MEN1 | |
| SCHEMBL11414067 | 0.77 | KMT2A (0.45) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10448028 | 0.75 | MAPT (0.54) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL742856 | 0.74 | ALDH1A1 (0.39) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1955043 | 0.74 | MAPT (0.52) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11404623 | 0.74 | MAPT (0.52) | MAPTHTTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098608-A1 | PYRAZOLO [4, 3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS OF USE | ÚSTAV EXPERIMENTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2004-11-18 | — | — | WO | disclosed |