SCHEMBL742856

SCHEMBL742856

FC(F)(F)ONc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
TDP1 Q9NUW8 3/20 0.39
HSD17B10 Q99714 2/20 0.39
CTSD P07339 1/20 0.39
PDK1 Q15118 2/20 0.38
PDK2 Q15119 2/20 0.38
PDK3 Q15120 2/20 0.38
PDK4 Q16654 2/20 0.38
TSHR P16473 3/20 0.38
PTGS2 P35354 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
MAPK1 P28482 1/20 0.38
HTR2B P41595 1/20 0.38
MAPT P10636 4/20 0.37
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27973589 0.89 TSHR (0.44) ALDH1A1TDP1CTSDPDK1PDK2
SCHEMBL31114495 0.88 PDK1 (0.36) ALDH1A1TDP1HSD17B10CTSDPDK1
SCHEMBL28285341 0.88 PDK1 (0.43) ALDH1A1HSD17B10PDK1PDK2PDK3
SCHEMBL5716690 0.87 KIF11 (0.45) ALDH1A1TDP1HSD17B10MAPK1MAPT
SCHEMBL28599363 0.83 ALDH1A1 (0.44) ALDH1A1TDP1CTSDPDK1PDK2
SCHEMBL15391808 0.81 ALDH1A1 (0.36) ALDH1A1TDP1HSD17B10CTSDPDK1
Thiomorpholine SCHEMBL11884508 0.80 CYP2D6 (0.32) SLC6A2CYP2D6
SCHEMBL31019388 0.80 KIF11 (0.40) L3MBTL1MAPTHDAC1HDAC7HDAC8
SCHEMBL2493371 0.79 ALDH1A1 (0.35) ALDH1A1TDP1HSD17B10CTSDPDK1
SCHEMBL11404016 0.78 ALDH1A1 (0.35) ALDH1A1MAPK1MAPTIDO1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 475 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114324620-B Method for detecting p-trifluoromethoxy aniline and related impurities 鲁南制药集团股份有限公司 2024-10-11 CN claimed
CN-117986438-A Super-wetting fluorine-containing acrylate applied to anti-fouling paint and preparation method thereof 安徽徽邦漆业有限公司 2024-05-07 CN claimed
CN-117049969-A Preparation method of 2, 6-dibromo-4-trifluoromethoxy aniline 阜新睿光氟化学有限公司 2023-11-14 CN claimed
CN-111777535-B Fluorine-containing azo surfactant prepared by clicking mercapto-alkene and method 济南大学 2022-06-24 CN claimed
CN-113940356-A Indoxacarb microemulsion and preparation method thereof 安徽广信农化股份有限公司 2022-01-18 CN claimed
CN-112479934-A Synthesis method of methyl amino chloroformate 安徽广信农化股份有限公司 2021-03-12 CN claimed
CN-111777535-A Fluorine-containing azo surfactant prepared by clicking mercapto-alkene and method 济南大学 2020-10-16 CN claimed
CN-109134277-B Synthetic method of p-trifluoromethoxyaniline as insecticide metaflumizone intermediate 山东省农药科学研究院 2020-01-03 CN claimed
CN-109916887-A A kind of colorimetric detection method of primaquine class drug 广州中医药大学(广州中医药研究院) 2019-06-21 CN claimed
CN-108101147-B Method for catalytic degradation of chemical wastewater by novel catalytic material 山东锐华氟业有限公司 2019-05-24 CN claimed
EP-1066022-A1 COMPOSITIONS FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC COUPLER, NOVEL CATIONIC COUPLERS, THEIR USE FOR OXIDATION DYEING AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP claimed
EP-1066264-A2 NOVEL CATIONIC 2-SULPHONYLAMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP claimed
EP-1066263-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP claimed
EP-1066246-A1 NOVEL CATIONIC COUPLERS AND THEIR USE FOR OXIDATION DYEING L'OREAL (FR) 2001-01-10 EP claimed
WO-2000042979-A1 COMPOSITIONS FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC COUPLER, NOVEL CATIONIC COUPLERS, THEIR USE FOR OXIDATION DYEING AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO claimed
WO-2000043368-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO claimed
WO-2000042971-A2 NOVEL CATIONIC 2-SULPHONYLAMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO claimed
WO-2000043356-A1 NOVEL CATIONIC COUPLERS AND THEIR USE FOR OXIDATION DYEING L'OREAL (FR) 2000-07-27 WO claimed
EP-0546391-A2 Process for the preparation of fluorine containing anilines. BAYER AG (DE) 1993-06-16 EP claimed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP claimed