Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705398 | 0.83 | KDR (0.42) | KDR | |
| SCHEMBL5744563 | 0.75 | KDR (0.52) | KDRFFAR2 | |
| SCHEMBL26647051 | 0.72 | DUT (0.32) | — | |
| SCHEMBL26646832 | 0.72 | P2RX7 (0.37) | — | |
| SCHEMBL5745081 | 0.69 | KDR (0.57) | KDR | |
| SCHEMBL6700794 | 0.68 | KDR (0.46) | KDR | |
| SCHEMBL26647084 | 0.64 | — | — | |
| SCHEMBL5742382 | 0.64 | KDR (0.48) | KDR | |
| SCHEMBL5744213 | 0.62 | KDR (0.58) | KDRFFAR2 | |
| SCHEMBL5741877 | 0.62 | KDR (0.61) | KDRFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235867-A1 | Tyrosine kinase inhibitors | BILODEAU MARK T (US) | 2004-11-25 | — | — | US | disclosed |
| WO-2003009852-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235867-A1 | Tyrosine kinase inhibitors | ERBB2, TYRO3, TIE1 | KDR 5/4885FFAR2 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.