Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 11/20 | 0.66 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.66 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.66 |
| ▸ | CLK2 | P49760 | 3/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | CDK8 | P49336 | 2/20 | 0.46 |
| ▸ | PRKX | P51817 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702968 | 0.77 | FGFR1 (0.71) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL28104327 | 0.75 | FGFR1 (0.65) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL8264120 | 0.75 | FGFR1 (0.70) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL2460902 | 0.74 | FGFR1 (1.00) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL8266373 | 0.72 | FGFR1 (0.70) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL16711157 | 0.70 | MAPT (0.49) | FGFR1FGFR2FGFR3DYRK1AROCK2 | |
| SCHEMBL13115655 | 0.70 | FGFR1 (0.71) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL16935421 | 0.69 | FGFR1 (1.00) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL10269367 | 0.69 | FGFR1 (0.55) | FGFR1FGFR2FGFR3CLK2CLK4 | |
| SCHEMBL2461196 | 0.68 | FGFR1 (0.64) | FGFR1FGFR2FGFR3CLK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220248-A1 | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE | KANIA ROBERT STEVEN (US) | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220248-A1 | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE | CDK3, BRAF, ROCK1 | FGFR1 262/4885FGFR2 583/4885FGFR3 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.