⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uracil SCHEMBL28946101 | 0.97 | CRBN (0.90) | — | |
| Uracil SCHEMBL5089507 | 0.97 | — | — | |
| Uracil SCHEMBL3798527 | 0.97 | CRBN (1.00) | — | |
| Uracil SCHEMBL8235 | 0.97 | — | — | |
| Uracil SCHEMBL2161716 | 0.94 | — | — | |
| Uracil SCHEMBL2557975 | 0.94 | — | — | |
| Uracil SCHEMBL18010636 | 0.94 | — | — | |
| Uracil SCHEMBL710130 | 0.94 | — | — | |
| Uracil SCHEMBL16116311 | 0.94 | — | — | |
| Uracil SCHEMBL8767625 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171046-A1 | Method for monitoring the transition of a cell from one state into another | EPIGENOMICS AG (DE) | 2004-09-02 | — | — | US | claimed |
| EP-1428889-A1 | Method for monitoring the transition of a cell from one state into another | Epigenomics AG (DE) | 2004-06-16 | — | — | EP | claimed |
| EP-1332756-A2 | Compositions and methods for restoring a normal pattern of imprinting to cells | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2003-08-06 | — | — | EP | claimed |
| JP-2001507703-A | — | — | 2001-06-12 | — | — | JP | claimed |
| EP-0969822-A2 | COMPOSITIONS AND METHODS FOR RESTORING A NORMAL PATTERN OF IMPRINTING TO CELLS | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1998029108-A2 | COMPOSITIONS AND METHODS FOR RESTORING A NORMAL PATTERN OF IMPRINTING TO CELLS | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1998-07-09 | — | — | WO | claimed |
| US-4419351-A | ANTITUMOR AGENTS | RESEARCH CORPORATION (US) | 1983-12-06 | — | — | US | claimed |
| US-20040171046-A1 | Method for monitoring the transition of a cell from one state into another | EPIGENOMICS AG (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1428889-A1 | Method for monitoring the transition of a cell from one state into another | Epigenomics AG (DE) | 2004-06-16 | — | — | EP | disclosed |
| EP-1332756-A2 | Compositions and methods for restoring a normal pattern of imprinting to cells | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2003-08-06 | — | — | EP | disclosed |
| EP-0969822-B1 | DETERMINATION OF THE PROPENSITY OF AN ORGAN OR TISSUE FOR CANCER BY DETERMINING OF ITS IMPRINTING PATTERN | UNIV JOHNS HOPKINS MED (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-0969822-A2 | COMPOSITIONS AND METHODS FOR RESTORING A NORMAL PATTERN OF IMPRINTING TO CELLS | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998029108-A2 | COMPOSITIONS AND METHODS FOR RESTORING A NORMAL PATTERN OF IMPRINTING TO CELLS | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1998-07-09 | — | — | WO | disclosed |
| US-4419351-A | ANTITUMOR AGENTS | RESEARCH CORPORATION (US) | 1983-12-06 | — | — | US | disclosed |
| US-4419351-A | ANTITUMOR AGENTS | RESEARCH CORPORATION (US) | 1983-12-06 | — | — | US | disclosed |
| US-4419351-A | ANTITUMOR AGENTS | RESEARCH CORPORATION (US) | 1983-12-06 | — | — | US | disclosed |