Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11954971 | 0.81 | LOXL2 (0.58) | LOXL2NCF1AAK1FERMT2HTR1A | |
| SCHEMBL23496972 | 0.78 | LOXL2 (0.55) | LOXL2NCF1FERMT2HTR1AADRA1D | |
| SCHEMBL263790 | 0.75 | LOXL2 (1.00) | LOXL2NCF1FERMT2HTR1AADRA1D | |
| SCHEMBL30119619 | 0.75 | CYP1A2 (0.46) | CYP2D6CYP1A2LMNA | |
| SCHEMBL28157122 | 0.74 | LOXL2 (0.58) | LOXL2NCF1FERMT2HTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL3643761 | 0.73 | LOXL2 (0.96) | LOXL2NCF1FERMT2HTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL1208908 | 0.73 | LOXL2 (0.96) | LOXL2NCF1FERMT2HTR1AADRA1D | |
| SCHEMBL6017487 | 0.73 | NR3C1 (0.49) | LOXL2NCF1AAK1FERMT2HTR1A | |
| SCHEMBL28292734 | 0.72 | LOXL2 (0.47) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL6223283 | 0.72 | LOXL2 (0.71) | LOXL2NCF1FERMT2HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | LOXL2 3020/4885NCF1 3363/4885AAK1 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.