SCHEMBL6703734

SCHEMBL6703734

Cc1c(-c2ccccc2)cc2ccccc2c1-c1c(C)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 9/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 2/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
MPI P34949 1/20 0.48
ALOX5 P09917 1/20 0.46
RECQL P46063 1/20 0.45
SQOR Q9Y6N5 1/20 0.43
MAOB P27338 1/20 0.42
RAB9A P51151 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP11B1 P15538 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31275918 1.00 GPR84 (0.51) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL28296648 0.94 GPR84 (0.50) GPR84MEN1KMT2AKDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL28620560 0.84 MEN1 (0.48) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL12583065 0.83 GPR84 (0.59) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL3182959 0.82 MEN1 (0.47) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL12583233 0.82 GPR84 (0.41) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL12583223 0.81 CA1 (0.45) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL12583246 0.81 GPR84 (0.45) GPR84MEN1KMT2AKDM4EMAPT
SCHEMBL11906312 0.81 MEN1 (0.55) GPR84MEN1KMT2AKDM4EALDH1A1
SCHEMBL12583245 0.80 GPR84 (0.61) GPR84KMT2AALDH1A1HPGDALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040072680-A1 Chiral phosphorus cyclic compounds for transition metal-catalyzed asymmetric reactions THE PENN STATE RESEARCH FOUNDATION 2004-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040072680-A1 Chiral phosphorus cyclic compounds for transition metal-catalyzed asymmetric reactions PNKP, PIK3CA, GNPAT GPR84 3570/4885MEN1 2555/4885KMT2A 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.