Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703734 | 0.94 | GPR84 (0.51) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL31275918 | 0.94 | GPR84 (0.51) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL3182959 | 0.85 | MEN1 (0.47) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL14677000 | 0.82 | CYP1A2 (0.45) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL29654725 | 0.82 | CYP1A2 (0.45) | GPR84MEN1KMT2AKDM4EALOX5 | |
| Ammonia Solution, Strong SCHEMBL28620560 | 0.82 | MEN1 (0.48) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL4780472 | 0.82 | GPR84 (0.54) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL31756884 | 0.82 | GPR84 (0.54) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL25418827 | 0.80 | ALOX5 (0.48) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL24578983 | 0.79 | ALOX5 (0.41) | GPR84MEN1KMT2AKDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843856-A | KRAS G12C inhibitor | 米拉蒂治疗股份有限公司 | 2019-06-04 | — | — | CN | disclosed |