SCHEMBL6703755

SCHEMBL6703755

O=C(O)c1c(Cl)n(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.62
ALDH1A1 P00352 5/20 0.62
LMNA P02545 5/20 0.62
HPGD P15428 4/20 0.62
HSD17B10 Q99714 4/20 0.62
CYP1A2 P05177 1/20 0.62
TOP2A P11388 1/20 0.62
CYP2C9 P11712 1/20 0.62
TOP2B Q02880 1/20 0.62
BRD4 O60885 1/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.52
CYP2J2 P51589 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
PRKD3 O94806 1/20 0.46
PIM1 P11309 1/20 0.46
GSK3A P49840 1/20 0.46
GSK3B P49841 1/20 0.46
IRAK1 P51617 1/20 0.46
RPS6KA3 P51812 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30866391 0.88 KDM4E (0.63) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL3673753 0.86 ALDH1A1 (0.60) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL2764444 0.85 KDM4E (0.59) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL30686874 0.85 ALDH1A1 (0.59) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL6863234 0.84 ALDH1A1 (0.58) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL9014024 0.83 PRKD3 (0.40) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL30448428 0.82 ALDH1A1 (0.58) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL6790985 0.81 ALDH1A1 (0.61) KDM4EALDH1A1LMNAHPGDHSD17B10
SCHEMBL6864144 0.80 ALDH1A1 (0.54) KDM4EALDH1A1LMNAHPGDHSD17B10
Hydrochloric Acid SCHEMBL6248075 0.80 KDM4E (0.60) KDM4EALDH1A1LMNAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112986468-B Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2024-05-03 CN claimed
CN-112986468-A Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2021-06-18 CN claimed
US-12005070-B2 Protective agent for keratoconjunctiva or suppressive agent for keratoconjunctival disorder TOYO SUGAR REFINING CO., LTD. (JP) 2024-06-11 US disclosed
CN-112986468-B Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2024-05-03 CN disclosed
CN-112986468-B Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2024-05-03 CN disclosed
CN-112986468-B Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2024-05-03 CN disclosed
CN-112986468-A Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2021-06-18 CN disclosed
CN-112986468-A Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2021-06-18 CN disclosed
CN-112986468-A Analysis method for detecting ciprofloxacin chloride in ciprofloxacin hydrochloride tablet 武汉九州钰民医药科技有限公司 2021-06-18 CN disclosed
EP-2783689-B1 KERATOCONJUNCTIVAL PROTECTING AGENT, OR KERATOCONJUNCTIVAL DISORDER INHIBITING AGENT TOYO SUGAR REFINING CO LTD (JP) 2019-09-25 EP disclosed
US-20160367584-A1 PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER TOYO SUGAR REFINING CO., LTD. (JP) 2016-12-22 US disclosed
EP-2987787-A1 NOVEL COMPOUND WITH ANTIBACTERIAL ACTIVITY Juntendo Educational Foundation (JP) 2016-02-24 EP disclosed
EP-2500022-B1 ANTIBACTERIAL AGENT FOR DRUG-RESISTANT BACTERIA AND USE OF SAME MICROBIAL CHEM RES FOUND (JP) 2015-12-16 EP disclosed
US-20150322033-A1 ANTIBACTERIAL AGENT JUNTENDO EDUCATIONAL FOUNDATION (JP) 2015-11-12 US disclosed
US-20140315836-A1 PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER TOYO SUGAR REFINING CO., LTD. (JP) 2014-10-23 US disclosed
EP-2783689-A1 KERATOCONJUNCTIVAL PROTECTING AGENT, OR KERATOCONJUNCTIVAL DISORDER INHIBITING AGENT Toyo Sugar Refining Co., Ltd. (JP) 2014-10-01 EP disclosed
US-20120258980-A1 Antibacterial Agent for Drug-Resistant Bacteria, Method for Screening for Same, and Use of Same MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 2012-10-11 US disclosed
EP-2500022-A1 ANTIBACTERIAL AGENT FOR DRUG-RESISTANT BACTERIA, METHOD FOR SCREENING FOR SAME, AND USE OF SAME Microbial Chemistry Research Foundation (JP) 2012-09-19 EP disclosed
CN-101244065-A Combined sustained-release agent for preventing and controlling livestock coccidiosis and bacillary dysentery, and preparation thereof ZHEJIANG ACAD AGRICULTURAL SCI (CN) 2008-08-20 CN disclosed
US-20040034042-A1 Preservative composition ROHTO PHARMACEUTICAL CO., LTD. (JP) 2004-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367584-A1 PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER UGCG, GBA1, GOLGA2 KDM4E 2512/4885ALDH1A1 1942/4885LMNA 1761/4885
US-20140315836-A1 PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER UGCG, GBA1, GOLGA2 KDM4E 2512/4885ALDH1A1 1942/4885LMNA 1761/4885
US-20040034042-A1 Preservative composition XDH, XPA, SORBS1 KDM4E 2017/4885ALDH1A1 714/4885LMNA 17/4885
US-12005070-B2 Protective agent for keratoconjunctiva or suppressive agent for keratoconjunctival disorder UGCG, GBA1, GOLGA2 KDM4E 2512/4885ALDH1A1 1942/4885LMNA 1761/4885
US-20120258980-A1 Antibacterial Agent for Drug-Resistant Bacteria, Method for Screening for Same, and Use of Same NRDC, DNAJB12, MGAM KDM4E 4158/4885ALDH1A1 3130/4885LMNA 4009/4885
US-20150322033-A1 ANTIBACTERIAL AGENT Q6ZSR9, MRPL21, NQO2 KDM4E 3156/4885ALDH1A1 2088/4885LMNA 4085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.