Phenanthrene

Phenanthrene

SCHEMBL670439

C=C(C)C(=O)O.C=C(C)C(=O)O.c1ccc2c(c1)ccc1ccccc12

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
HPGD P15428 4/20 0.53
MAPT P10636 2/20 0.53
HSD17B10 Q99714 6/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP2A6 P11509 1/20 0.52
KDM4E B2RXH2 4/20 0.49
LMNA P02545 1/20 0.49
WDR5 P61964 1/20 0.48
HPRT1 P00492 1/20 0.48
LDHA P00338 1/20 0.47
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
KMT2A Q03164 1/20 0.46
PAX8 Q06710 1/20 0.45
GLA P06280 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthrene SCHEMBL27623638 1.00 ALDH1A1 (0.53) ALDH1A1HPGDMAPTHSD17B10TSHR
Methacrylic Acid SCHEMBL17206137 0.96 HPRT1 (0.56) ALDH1A1HPGDMAPTHSD17B10TSHR
Triphenylene SCHEMBL29117647 0.86 KDM4E (0.47) ALDH1A1HPGDMAPTHSD17B10TSHR
Naphthalene SCHEMBL3422143 0.86 KDM4E (0.47) ALDH1A1HPGDMAPTHSD17B10TSHR
Phenanthrene SCHEMBL11152558 0.86 ALDH1A1 (0.63) ALDH1A1HPGDMAPTHSD17B10TSHR
Naphthalene SCHEMBL3422961 0.86 KDM4E (0.47) ALDH1A1HPGDMAPTHSD17B10TSHR
Naphthalene SCHEMBL2138200 0.86 KDM4E (0.47) ALDH1A1HPGDMAPTHSD17B10TSHR
Methacrylic Acid SCHEMBL23795396 0.86 CYP2C9 (0.48) ALDH1A1HPGDKDM4ENR4A1NR4A2
Methacrylic Acid SCHEMBL5612185 0.85 PTPN22 (0.66) ALDH1A1HPGDHSD17B10KDM4ELDHA
1-Naphthol SCHEMBL2192629 0.84 CYP1A2 (0.63) ALDH1A1HPGDMAPTHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63233952-A None JP disclosed
CN-103025773-B Polymerizable mixture and use thereof in liquid crystal displays MERCK PATENT GMBH 2015-07-15 CN disclosed
EP-2596034-B1 POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2014-11-26 EP disclosed
CN-101978025-B Liquid-crystal display MERCK PATENT GMBH 2014-09-10 CN disclosed
EP-2596034-A2 POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS Merck Patent GmbH (DE) 2013-05-29 EP disclosed
CN-103025773-A Polymerizable mixture and use thereof in liquid crystal displays MERCK PATENT GMBH 2013-04-03 CN disclosed
WO-2012022391-A2 POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2012-02-23 WO disclosed
CN-101978025-A Liquid-crystal display MERCK PATENT GMBH 2011-02-16 CN disclosed
WO-2009118086-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-10-01 WO disclosed
JP-S63233952-A PHENANTHRENE COMPOUND NIPPON STEEL CHEM CO LTD 1988-09-29 JP disclosed