Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PLTP | P55058 | 2/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702247 | 0.95 | RXFP1 (0.37) | MAPTALDH1A1RXFP1PLTPTRPV4 | |
| SCHEMBL6703995 | 0.93 | MAPT (0.41) | MAPTALDH1A1RXFP1HSD17B10PLTP | |
| SCHEMBL6705254 | 0.88 | TRPV4 (0.33) | MAPTALDH1A1RXFP1PLTPTRPV4 | |
| SCHEMBL6703725 | 0.88 | MAPT (0.34) | MAPTALDH1A1RXFP1PLTPTRPV4 | |
| SCHEMBL6699876 | 0.88 | PTGDR2 (0.35) | MAPTALDH1A1RXFP1PLTPTRPV4 | |
| SCHEMBL7087093 | 0.87 | MAPT (0.39) | MAPTALDH1A1RXFP1HSD17B10HPGD | |
| SCHEMBL6704678 | 0.86 | MAPT (0.39) | MAPTALDH1A1RXFP1HSD17B10HPGD | |
| SCHEMBL27581733 | 0.86 | TRPV4 (0.34) | MAPTALDH1A1PLTPTRPV4HPGD | |
| SCHEMBL7686931 | 0.83 | TRPV4 (0.35) | MAPTPLTPTRPV4TP53LMNA | |
| SCHEMBL7683689 | 0.83 | TRPV4 (0.35) | MAPTRXFP1PLTPTRPV4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |