Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PLTP | P55058 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683689 | 0.95 | TRPV4 (0.35) | TRPV4SAE1MAPTPDE4APDE4B | |
| SCHEMBL6702896 | 0.94 | MAPT (0.34) | TRPV4SAE1MAPTALDH1A1HPGD | |
| SCHEMBL7686931 | 0.90 | TRPV4 (0.35) | TRPV4SAE1MAPTPDE4APDE4B | |
| SCHEMBL6703725 | 0.89 | MAPT (0.34) | TRPV4MAPTALDH1A1HPGDPLTP | |
| SCHEMBL6704667 | 0.89 | TRPV4 (0.33) | TRPV4SAE1MAPTALDH1A1HPGD | |
| SCHEMBL6704419 | 0.88 | MAPT (0.39) | TRPV4MAPTALDH1A1HPGDPLTP | |
| SCHEMBL7679717 | 0.88 | MEN1 (0.40) | TRPV4MAPTALDH1A1HPGDPLTP | |
| SCHEMBL7688378 | 0.87 | MEN1 (0.38) | TRPV4MAPTPDE4APDE4BPDE4C | |
| SCHEMBL7688220 | 0.87 | TRPV4 (0.35) | TRPV4MAPTPLTPTP53LMNA | |
| SCHEMBL6705251 | 0.86 | SAE1 (0.34) | SAE1MAPTALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |